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Registro Completo |
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Biblioteca(s): |
Embrapa Unidades Centrais. |
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Data corrente: |
02/05/2016 |
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Data da última atualização: |
29/12/2017 |
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Autoria: |
OLIVEIRA, D. M.; HAGEN, S. C.; SANTOS, A. C.; MIGLINO, M. A.; ASSIS NETO, A. C. |
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Afiliação: |
DANIELA M. OLIVEIRA, USP; STEFANO C. HAGEN, USP; AMILTON C. SANTOS, USP; MARIA A. MIGLINO, USP; ANTÔNIO C. ASSIS NETO, USP. |
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Título: |
Noninvasive evaluation of respiratory muscles in pre-clinical model of Duchenne Muscular Dystrophy. |
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Ano de publicação: |
2016 |
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Fonte/Imprenta: |
Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 36, n. 4, p. 290-296, abr. 2016. |
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Idioma: |
Inglês |
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Conteúdo: |
Since respiratory insufficiency is the main cause of death in patients affected by Duchenne Muscular Dystrophy (DMD), the present study aims at establishing a new non-invasive method to evaluate the clinical parameters of respiratory conditions of experimental models affected by DMD. With this purpose in mind, we evaluated the cardiorespiratory clinical conditions, the changes in the intercostal muscles, the diaphragmatic mobility, and the respiratory cycles in Golden Retriever Muscular Dystrophy (GRMD) employing ultrasonography (US). A control group consisting of dogs of the same race, but not affected by muscular dystrophy, were used in this study. The results showed that inspiration, expiration and plateau movements (diaphragm mobility) were lower in the affected group. Plateau phase in the affected group was practically non-existent and showed that the diaphragm remained in constant motion. Respiratory rate reached 15.5 per minute for affected group and 26.93 per minute for the control group. Expiration and inspiration movements of intercostal muscles reached 8.99mm and 8.79mm, respectively, for control group and 7.42mm and 7.40mm, respectively, for affected group. Methodology used in the present analysis proved to be viable for the follow-up and evaluation of the respiratory model in GRMD and may be adapted to other muscular dystrophy experimental models. |
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Palavras-Chave: |
Distrofia Muscular de Duchenne; DMD; Duchenne Muscular Dystrophy; GRMD; Músculos respiratório; Respiratory muscles. |
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Thesagro: |
Diafragma; Ultrassom. |
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Thesaurus Nal: |
Diaphragm; Ultrasonics. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/142692/1/Noninvasive-evaluation.pdf
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Marc: |
LEADER 02230naa a2200289 a 4500
001 2044291
005 2017-12-29
008 2016 bl uuuu u00u1 u #d
100 1 $aOLIVEIRA, D. M.
245 $aNoninvasive evaluation of respiratory muscles in pre-clinical model of Duchenne Muscular Dystrophy.
260 $c2016
520 $aSince respiratory insufficiency is the main cause of death in patients affected by Duchenne Muscular Dystrophy (DMD), the present study aims at establishing a new non-invasive method to evaluate the clinical parameters of respiratory conditions of experimental models affected by DMD. With this purpose in mind, we evaluated the cardiorespiratory clinical conditions, the changes in the intercostal muscles, the diaphragmatic mobility, and the respiratory cycles in Golden Retriever Muscular Dystrophy (GRMD) employing ultrasonography (US). A control group consisting of dogs of the same race, but not affected by muscular dystrophy, were used in this study. The results showed that inspiration, expiration and plateau movements (diaphragm mobility) were lower in the affected group. Plateau phase in the affected group was practically non-existent and showed that the diaphragm remained in constant motion. Respiratory rate reached 15.5 per minute for affected group and 26.93 per minute for the control group. Expiration and inspiration movements of intercostal muscles reached 8.99mm and 8.79mm, respectively, for control group and 7.42mm and 7.40mm, respectively, for affected group. Methodology used in the present analysis proved to be viable for the follow-up and evaluation of the respiratory model in GRMD and may be adapted to other muscular dystrophy experimental models.
650 $aDiaphragm
650 $aUltrasonics
650 $aDiafragma
650 $aUltrassom
653 $aDistrofia Muscular de Duchenne
653 $aDMD
653 $aDuchenne Muscular Dystrophy
653 $aGRMD
653 $aMúsculos respiratório
653 $aRespiratory muscles
700 1 $aHAGEN, S. C.
700 1 $aSANTOS, A. C.
700 1 $aMIGLINO, M. A.
700 1 $aASSIS NETO, A. C.
773 $tPesquisa Veterinária Brasileira, Rio de Janeiro$gv. 36, n. 4, p. 290-296, abr. 2016.
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Embrapa Unidades Centrais (AI-SEDE) |
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| Registros recuperados : 3 | |
| 1. |  | MIRANDA, S. DO C. DE; BUSTAMANTE, M.; PALACE, M.; HAGEN, S.; KELLER, M.; FERREIRA, L. G. Regional Variations in Biomass Distribution in Brazilian Savanna Woodland. Biotropica, v. 46, n. 2, p. 125-138, 2014. Artigo publicado por Pesquisador Visitante da Embrapa Monitoramento por Satélite.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Territorial. |
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| 2. | | OLIVEIRA, D. M.; HAGEN, S. C.; SANTOS, A. C.; MIGLINO, M. A.; ASSIS NETO, A. C. Noninvasive evaluation of respiratory muscles in pre-clinical model of Duchenne Muscular Dystrophy. Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 36, n. 4, p. 290-296, abr. 2016.| Biblioteca(s): Embrapa Unidades Centrais. |
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| 3. | | LATORRE, S. M.; BONOMO, C. C. M.; MICHIMA, L. E. S.; HAGEN, S. C. F.; FERNANDES, W. R. Índice e dimensões ecocardiográficas de equinos da raça Mangalarga Marchador. Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 36, n. 6, p. 533-538, junho. 2016.| Biblioteca(s): Embrapa Unidades Centrais. |
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| Registros recuperados : 3 | |
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